Afecta Pharmaceuticals, Inc. is a patient-inspired, physician-driven pharmaceutical company focused on discovering and developing new medicines to treat immune-mediated diseases.
Our vision is to be an industry leader in creating new and more effective small molecule drugs based on safe, existing compounds.
Afecta was founded by physician-scientists at the University of Southern California, City of Hope/Beckman Research Institute, University of California Irvine, and the California Institute of Technology, who were studying the role of genetics and the actions of drugs on human diseases. Afecta’s founders recognized correlations between the underlying genetic differences among different patient groups and their differential drug-response. Inspired by their patients, especially women and children who were underserved by the pharmaceutical industry, and passionate about improving their health and quality of life, Afecta’s founders began de-convoluting the symptoms and uncovering the underlying mechanisms of diseases from which their patients suffered. This passion for improving the treatments they could offer their patients led Afecta’s founders to develop novel methods and a comprehensive drug discovery platform to classify diseases, sub-type patient groups, identify key disease pathways, and discover new drugs to more safely and effectively treat these disorders. The first drug developed by Afecta was licensed to Supernus (NASDAQ: SUPN) and was granted fast-track approval by the FDA and is currently in the final phase III clinical trial.